Andy M Lau
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Antibiotic resistance
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB
[Nature Communications] Resistance–nodulation–division efflux pumps play a key role in inherent and evolved multidrug resistance in bacteria. AcrB, a prototypical member of this protein family, extrudes a wide range of antimicrobial agents out of …
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